In press (accepted papers)

(1) Anca Diana Cristea, Marcela Popa, Mariana Carmen Chirifiuc, Luminita Marutescu, Veronica Lazar,  Ioana Suciu, Andrei Iliescu, Bogdan Dimitriu, Paula Perlea: The antimicrobial efficiency of endodontic irrigation solutions on bacterial biofilm. A literature review

Abstract: The purpose of endodontic treatmentis the prevention or the removal of endodontic system infection, namely the chronic apical periodontitis, either by cutting down the access of the microorganisms in the root canal or by removing them completely However, despite all the efforts for the correct enlargement and irrigation of the root canal, several studies have shown that microorganisms from the endodontic system cannot be entirely eliminated due to the biofilm characteristics at this level, which are different from those of planktonic cells and single cells, but also due to the morphology of the endododontic area, which features several microspaces such as side channels, isthmi, apical ramifications, anastomoses, all of them favouring the development and persistance of bacterial biofilm. Various medical substances have proved to be effective in eradicating planktonic bacteria in vitro. But since the internal environment of the tooth reduces the activity of irrigants substantially, thereare also failure rates in obtainingpredictable results in this aspect. The purpose of this review is to assess the efficiency of chlorhexidine and sodium hypochlorite, used as irrigant solutions, against the endodontic biofilm development.